Sesbania grandiflora

Family: Fabaceae


Family Synonyms

Common Names

Bakful(Bengali), Agasti(Bengali), Agati(Bengali), Bak(Bengali), Sai Sha(Marma)

Local Availability

Throughtout Bangladesh

Worldwide Availability

Botanical Description 22

A small. Slender deciduous tree, 6-9m high, with a straight trunk and light crown. Leaves 15-30cm long; leaflets 16-30 pairs, linear-oblong. Racemes 2.5cm long, bearing 2-4 large, white flowers; corol

Common Ethnobotanical Use 23

The Bark is astringent and tonic; infusion is used in diarrhea, dysentery and paludism. The leaves are tonic, antipyretic, anthelmintic and alexiteric; cures itching, leprosy, night blindness, gout and biliousness. The flowers are cooling, emollient and laxative; improves the appetite; useful in ozoena, bronchitis, gout. The juice of leaves or flowers is a popular remedy in nasalcatarrh and headache. Fruits are alexeteric and laxative; cures fever, pains, bronchitis. Root juice is with honey as an expectorant in catarrh. Root paste of the red-flowered variety is applied in rheumatism

Chemical Constituents

Compound Name Compound in Plant Parts Reference
Oleanolic acidFlower1
Betulinic acidRoot4
IsovestitolRoot3, 4
SativanRoot3, 4

Pharmacological Evidence

Plants Parts Extract Type Activity Reference
N/A Antiinflammatory 18
Ethanol Antiulcerant 21
N/A Antiarthritic 18
Methanol Leukemia 6
Phosphate Buffered Saline Anticancer 8
Alcohol Antidiabetic 9
Ethyl Acetate Antibacterial 14
Methanol Antimicrobial 15
Ethyl Acetate Antifungal 14
Methanol Antiinflammatory 17
Methanol Lung Cancer 5
Petroleum Ether Antidiabetic 10
Aqueous Antibacterial 12
Methanol Analgesic 16
Methanol CNS Depressant 16
Ethanol Antiulcerant 19
Petroleum Ether; Chloroform; Hydroalcohol Antiulcerant 20
Leaf; Flower
Ethanol Anticancer 7
Methanol Antidiabetic 11
Stem Bark
Ethanol; Ethyl acetate; ButanolĀ  Antibacterial 13


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  • 2 Lakshminarayana, R., Raju, M., Krishnakantha, T.P. and Baskaran, V. (2005) Determination of major carotenoids in a few Indian leafy vegetables by high-performance liquid chromatography. Journal of Agricultural and food chemistry, 53, 2838-2842.
  • 3 Hasan, N., Osman, H., Mohamad, S., Chong, W.K., Awang, K. and Zahariluddin, A.S.M. (2012) The chemical components of Sesbania grandiflora root and their antituberculosis activity. Pharmaceuticals, 5, 882-889.
  • 4 Osman, H., Chong, W.K., Awang, K. and Manshoor, N. (2012) Isolation and Characterisation of l, l'-binaphthalene-2, 2'-diol, A New Biaryl Natural Product from Sesbania grandiflora Root. Journal of Basic & Applied Sciences, 8.
  • 5 Pajaniradje, S., Mohankumar, K., Pamidimukkala, R., Subramanian, S. and Rajagopalan, R. (2014) Antiproliferative and apoptotic effects of Sesbania grandiflora leaves in human cancer cells. BioMed research international, 2014.
  • 6 Roy, R., Kumar, D., Chakraborty, B., Chowdhury, C. and Das, P. (2013) Apoptotic and autophagic effects of Sesbania grandiflora flowers in human leukemic cells. PLoS One, 8, e71672.
  • 7 Sreelatha, S., Padma, P. and Umasankari, E. (2011) Evaluation of anticancer activity of ethanol extract of Sesbania grandiflora (Agati Sesban) against Ehrlich ascites carcinoma in Swiss albino mice. Journal of ethnopharmacology, 134, 984-987.
  • 8 Laladhas, K.P., Cheriyan, V.T., Puliappadamba, V.T., Bava, S.V., Unnithan, R.G., Vijayammal, P.L. and Anto, R.J. (2010) A novel protein fraction from Sesbania grandiflora shows potential anticancer and chemopreventive efficacy, in vitro and in vivo. Journal of cellular and molecular medicine, 14, 636-646.
  • 9 Kumar, R., Janadri, S., Kumar, S. and Swamy, S. (2015) Evaluation of antidiabetic activity of alcoholic extract of flower Sesbania grandiflora in alloxan induced diabetic rats. Asian Journal of Pharmacy and Pharmacology, 1, 21-26.
  • 10 Sangeetha, A., Sriram Prasath, G. and Subramanian, S. (2014) Antihyperglycemic and antioxidant potentials of sesbania grandiflora leaves studied in stz induced experimental diabetic rats. International Journal of Pharmaceutical Sciences and Research, 5, 2266-2275.
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  • 12 Das, J., Das, M.P. and Velusamy, P. (2013) Sesbania grandiflora leaf extract mediated green synthesis of antibacterial silver nanoparticles against selected human pathogens. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 104, 265-270.
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  • 15 China, R., Mukherjee, S., Sen, S., Bose, S., Datta, S., Koley, H., Ghosh, S. and Dhar, P. (2012) Antimicrobial activity of Sesbania grandiflora flower polyphenol extracts on some pathogenic bacteria and growth stimulatory effect on the probiotic organism Lactobacillus acidophilus. Microbiological Research, 167, 500-506.
  • 16 Sutradhar, K.B. and Choudhury, N.F. (2012) Analgesic and CNS depressant activity of the crude extract of Sesbania grandiflora. International Current Pharmaceutical Journal, 1, 56-61.
  • 17 Loganayaki, N., Suganya, N. and Manian, S. (2012) Evaluation of edible flowers of agathi (Sesbania grandiflora L. Fabaceae) for in vivo anti-inflammatory and analgesic, and in vitro antioxidant potential. Food Science and Biotechnology, 21, 509-517.
  • 18 Patil, R.B., Nanjwade, B. and Manvi, F. (2011) Evaluation of anti-inflammatory and antiarthritic effect of sesbania grandiflora bark and fruit of Terminalia chebula in rats. International Journal of Pharmacology and Biological Sciences, 5, 37.
  • 19 Bhalke, R.D., Giri, M.A., Anarthe, S.J. and Pal, S.C. (2010) Antiulcer activity of the ethanol extract of leaves of Sesbania grandiflora (Linn.). International Journal of Pharmacy and Pharmaceutical Sciences, 2, 206-208.
  • 20 Naik, H.V., Chavan, N., Deshmukh, H.A., Chaskar, P.K. and More, N.S. (2012) Study of Antiulcer Activity of Leaves of Sesbania grandiflora Linn.(Fabaceae). Research Journal of Pharmacognosy and Phytochemistry, 4, 322.
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